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An example of a case with a psychiatric client where the nurse practitioner must be aware of the action of a medication is when dealing with clients with known history of changes in CYP2C19 genes. A change in CYP2C19 gene affects the metabolism of antipsychotic and antidepressant medications. For instance, there is a reduction in metabolism of aripiprazole, haloperidol lactate, and risperidone in clients with altered CYP2C19 gene. Therefore, comprehensive history taking prior to administration of medications is important.
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